PSC Partners Seeking a Cure is pleased to present Living With
PSC, a podcast moderated by Niall McKay. Each month, this podcast
explores the latest research and knowledge about primary sclerosing
cholangitis (PSC), a rare liver disease. From patient stories, to
the latest research updates from PSC experts, to collaborations
that are necessary to find better treatments and a cure, this
podcast has it all!
In episode 25, Host Niall McKay talks with Dr. Gideon
Hirschfield about the use of antibiotics for the treatment of
infection in primary sclerosing cholangitis (PSC). Hirschfield says
that antibiotics are used for the treatment of intermittent,
symptomatic cholangitis in patients with PSC.
"There's no evidence that the long-term use of antibiotics
will change what ultimately happens to PSC patients," says Dr.
Hirschfield. "But there's definitely evidence that, once you've got
an infection, that drives PSC progression, which makes sense. Once
the biliary tree is inflamed, it's never the same."
McKay and Hirschfield touch on various PSC-related topics,
including research into new ways to treat PSC symptoms.
Dr. Hirschfield is the inaugural Lily and Terry Horner Chair
in Autoimmune Liver Disease Research at the Toronto Centre for
Liver Disease, Toronto General Hospital, and Professor of Medicine
in the Division of Gastroenterology at the University of Toronto.
As a clinician-scientist, Dr. Hirschfield manages a broad platform
of translational and trials-based clinical science with the goal of
advancing therapies for patients with inflammatory liver disease
that prevent the need for transplantation.